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Question

Rejection of tissue of organ transplants is brought about mainly by

A
Cytotoxic T cells
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B
NK cells
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C
Suppressor T cells
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D
B cells
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Solution

The correct option is A Cytotoxic T cells
T- cells plays a central role in cell-mediated immunity. Cytotoxic cells help to destroy the pathogens. These cells are also known as CD8+ T cells since they express the CD8 glycoprotein at their surfaces. These cells interact with the antigen presented by MHC complexes and releases cytokines to destroy it. During the transplant, it reacts to the transplanted organs by releasing cytokines which lead to rejection.
So, the correct answer is option A.

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