About 25 bp upstream of the transcription start site
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B
About 50 bp upstream of the transcription start site
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C
About 75 bp upstream of the transcription start site
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D
About 200 bp upstream of the transcription start site
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Solution
The correct option is A About 25 bp upstream of the transcription start site
A TATA box is a DNA sequence that indicates where a genetic sequence can be read and decoded. It is a type of promoter sequence, which specifies to other molecules where transcription begins. Transcription is a process that produces an RNA molecule from a DNA sequence. The TATA box is named for its conserved DNA sequence, which is most commonly TATAAA. Many eukaryotic genes have a conserved TATA box located 25-35 base pairs before the transcription start site of a gene. The TATA box is able to define the direction of transcription and also indicates the DNA strand to be read. Proteins called as transcription factors can bind to the TATA box and recruit an enzyme called as RNA polymerase, which synthesizes RNA from DNA.