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Introduction to Biotechnology

The given fig...

Question

The given figure represents the maturation of proinsulin into insulin. Identify the product A. [1]

a. Polypeptide A
b. Polypeptide B
c. Polypeptide C
d. Both (b) and (c)

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Solution

c. Polypeptide C [1 mark]

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(ii) C-polypeptide chain with 33 amino acids is removed prior to insulin formation.
(iii) Mature insulin is made up of 51 amino acids and arranged in two polypeptide chains-A and B.
(iv) Polypeptide chain A has 30 amino acids and polypeptide chain B has 21 amino acids.
(v) Polypeptide chains A and B are interconnected by only one S-S linkage.

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