The oxygen dissociation curve shifts to the right when
A
partial pressure of CO2 decreases
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B
partial pressure of CO2 increases
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C
partial pressure of O2 decreases
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D
pH of blood increases
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Solution
The correct option is B
partial pressure of CO2 increases
The strength with which oxygen binds to haemoglobin is affected by several factors. These factors shift or reshape the oxyhaemoglobin dissociation curve. A rightward shift indicates that the haemoglobin under study has a decreased affinity for oxygen. This could result from:
(i) an increase in partial pressure of carbon dioxide
(ii) an increase in acidity (decrease in pH) of blood
(iii) an increase in body temperature
(iv) an increase in 2,3-bisphosphoglycerate