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Question

What does the following equation represent? Explain p2+2pq+q2=1

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Solution

The given equation represents the gene frequency of the total population according to Hardy–Weinberg law. In this equation, suppose a gene has two alleles A and a and p is the frequency of occurrence of the dominant allele A and q is the frequency of occurrence of the recessive allele a in the parental generation. Then according to the equation,
p2 + 2pq + q2 = 1, where
p2 = frequency of occurrence of individuals with homozygous dominant alleles (AA)
2pq = frequency of occurrence of heterozygous individuals (Aa)
q2 = frequency of occurrence of individuals with homozygous recessive alleles (aa).
The sum total of all allelic frequencies is 1.


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