What is the effect of Rotenone on oxidative phosphorylation?

Inhibit complex II

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Inhibit complex I

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Inhibit ATPase

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Both I and II

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Solution

The correct option is B Inhibit complex I
Rotenone interrupts cellular respiration by blocking electron transport in mitochondria by inhibiting the enzyme NADH reductase(Respiratory Complex1).
So, the correct option is 'Inhibit complex I'.

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C_{3}

{[C r {(N H_{3})}_{2} C l_{2} (C_{2} O_{4})]}_{2}^{-}

	Column I		Column II
(a)	Chloramphenicol	(p)	Inhibits binding of aatRNA to ribosome
(b)	Erthromycin	(q)	Inhibits interaction between tRNA and mRNA
(c)	Neomycin	(r)	Inhibits initiation of translation
(d)	Streptomycin	(s)	Inhibits peptidyl transferase activity
(e)	Tetracycline	(t)	Inhibits translocation of mRNA over ribosome

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