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Question

What is the use of RNA silencing strategy?


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Solution

Silencing strategy:

  1. In higher plants and insects, RNA silencing is an evolutionarily conserved sequence-specific gene-inactivation system that also serves as an antiviral mechanism.
  2. Antiviral RNA silencing is overcome by viruses expressing silencing-suppressor proteins that can inhibit the host's antiviral silencing process.
  3. RNAi is the basis of virus-induced gene silencing (VIGS) in plants, implying that it plays a key role in disease resistance.
  4. The nematode parasite in the host plant is killed using an RNA silencing method.
  5. For example, Meloidogyne incognita, a nematode, can infect the roots of tobacco plants.

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