Which enzyme polymerizes RNA with defined sequence in a template independent manner?

Peptidyl transferase

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RNA Polymerase

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Reverse transcription

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Polynucleotide phosphorylase

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Solution

The correct option is D Polynucleotide phosphorylase
Polynucleotide phosphorylase polymerizes RNA with defined sequence in a template independent manner. PNPase is a bifunctional enzyme with a phosphorolytic 3' to 5' exoribonuclease activity and a 3'-terminal oligonucleotide polymerase activity.
So, the correct option is 'Polynucleotide phosphorylase'.

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