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Question
Which of the following diseases is not treated by inactivated 'Whole Agent Vaccine'?
Which of the following diseases is not treated by inactivated 'Whole Agent Vaccine'?
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Solution
The correct option is D Typhoid
- In 1896, heat-killed phenol preserved and acetone killed lyophilized injectable whole cell S. Typhi vaccine was generated.
- This inactivated whole-cell vaccine causes local inflammation, pain, systemic fever, malaise and disease-like symptoms.
- Thus, the whole cell inactivated vaccine was not considered suitable for public use and in spite of being licensed it is no longer available in the market.
- Most commonly used antibiotics for the treatment of typhoid fever are fluoroquinolones such as ciprofloxacin, ofloxacin and pefloxacin and third-generation cephalosporins such as ceftriaxone or cefotaxime.
- Hence, Typhoid is not treated by inactivated Whole Agent Vaccine.
- So, the correct answer is 'Typhoid'.
- In 1896, heat-killed phenol preserved and acetone killed lyophilized injectable whole cell S. Typhi vaccine was generated.
- This inactivated whole-cell vaccine causes local inflammation, pain, systemic fever, malaise and disease-like symptoms.
- Thus, the whole cell inactivated vaccine was not considered suitable for public use and in spite of being licensed it is no longer available in the market.
- Most commonly used antibiotics for the treatment of typhoid fever are fluoroquinolones such as ciprofloxacin, ofloxacin and pefloxacin and third-generation cephalosporins such as ceftriaxone or cefotaxime.
- Hence, Typhoid is not treated by inactivated Whole Agent Vaccine.
- So, the correct answer is 'Typhoid'.
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