Question

Which of the following does not react with sodium bisulphite ?

• A. III and IV
• B. II and IV
• C. I
• D. All reacts

Answer 1

The correct option is B

II and IV

In addition of sodium bisulphite, the nucleophile is bisulphite ion which, being a large ion, reacts only if C = O group is not sterically hindered. Thus $C{H}_{3}CO{C}_2{H}_5$ and $C_6{H}_{5}COC{H}_3$, having larger group like - $C{H}_{2}C{H}_3$ and $-C_6{H}_5$, do not react with $NaHS{0}_3$