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Question
Which of the following is a commercial blood cholesterol lowering agent?
Which of the following is a commercial blood cholesterol lowering agent?
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Solution
The correct option is C Statin
Statins are produced by the yeast Monascus purpureus. They act to lower blood-cholesterol levels by competitively inhibiting the enzyme which is essential for cholesterol synthesis.
In competitive inhibition, the inhibitor binds to the active site of the enzyme and blocks the binding of the actual substrate. It is called competitive inhibition, as the inhibitor competes with the actual substrate for the enzyme.
Statins are competitive inhibitors of HMG-CoA reductase, a key enzyme of cholesterol biosynthesis. These are structural analogs of the actual substrate for this enzyme and compete effectively to inhibit HMG-CoA reductase. Hence, they inhibit the synthesis of cholesterol and thereby lower blood cholesterol levels.
Streptokinase is modified by genetic engineering and is used as a clot buster that helps to dissolve clots in the blood vessels.
Cyclosporin A is an immunosuppressive agent that is administered to people who have undergone organ transplantation.
Lipase enzyme is used in detergent formulation. The enzyme removes oily stains on clothes.
Statins are produced by the yeast Monascus purpureus. They act to lower blood-cholesterol levels by competitively inhibiting the enzyme which is essential for cholesterol synthesis.
In competitive inhibition, the inhibitor binds to the active site of the enzyme and blocks the binding of the actual substrate. It is called competitive inhibition, as the inhibitor competes with the actual substrate for the enzyme.
Statins are competitive inhibitors of HMG-CoA reductase, a key enzyme of cholesterol biosynthesis. These are structural analogs of the actual substrate for this enzyme and compete effectively to inhibit HMG-CoA reductase. Hence, they inhibit the synthesis of cholesterol and thereby lower blood cholesterol levels.
Streptokinase is modified by genetic engineering and is used as a clot buster that helps to dissolve clots in the blood vessels.
Cyclosporin A is an immunosuppressive agent that is administered to people who have undergone organ transplantation.
Lipase enzyme is used in detergent formulation. The enzyme removes oily stains on clothes.
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