Question

Why is thalassemia major disease?

Answer 1

Thalassemia:

1. Thalassemia is an inherited blood disorder, which is caused because of a mutation in genes and affects the body’s ability to produce hemoglobin and red blood cells.
2. A person with thalassemia have very few red blood cells which may be very small and with very little hemoglobin.
3. In people with thalassemia, the bone marrow does not produce enough healthy hemoglobin or red blood cells, and the body breaks down these red blood cells with abnormal hemoglobin.
4. The red blood cells of people with thalassemia may not be flexible enough to squeeze through capillaries to reach necessary parts of the body.
5. In some minor cases, it can lead to a lack of oxygen which can cause anemia, fatigue and other blood deficiency syndromes, and in most of the cases, the person can experience iron overload, enlarged spleen, and bone deformities.
6. So, due to these reasons thalassemia is a major disease.