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Question

Write a brief note on Monogenic disorders. <!--td {border: 1px solid #ccc;}br {mso-data-placement:same-cell;}--> [Textbook question 5b pg no.193]


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Solution

Answer:
Pure genetic diseases caused in human DNA, by a single error in a single gene are monogenic disorders. A genetic disorder can be of three formes

  • Single gene disorder – one gene is affected (for example sickle cell anaemia).
  • Chromosomal disorders- the disorders in which chromosomes or parts of chromosomes are missing.
  • Complex disorders – In these disorders there are mutations in two or more genes.

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