Coagulation Cascade

Q.

What causes the right shift in the oxyhemoglobin dissociation curve?

Q. Which ion is required for the coagulation of blood?

1. Zinc
2. Copper
3. Magnesium
4. Calcium

Q.

Which enzyme is responsible for blood clotting?

Q.

Function of vitamin c and vitamin k with their chemical names

Q.

Which Cell Organelles Are Present In White Blood Cells?

Q. Which of the following is not a clotting factor in blood?

1. Prothrombin
2. Calcium
3. None of the above
4. Fibrinogen

Q. Which of the following statements is/are correct?

1. Clotting factors are activated by the damaged tissue outside the blood vessel only
2. Prothrombin is the inactive form of thrombin that is present in the plasma
3. The platelets outside the damaged blood vessel also activate a cascade of clotting factors
4. All of the above

Q. Which of the following are required for blood clotting?

1. $C{a}^{++}$, thromboplastin
2. $N{a}^{+},C{a}^{++}$
3. $K^{+}$, prothrombin
4. $K^{+}$, thromboplastin

Q. Vitamin K during blood coagulation is required for

1. change of fibrinogen to fibrin
2. change of prothrombin to thrombin
3. formation of prothrombin
4. all of the above

Q. we use alkaline phosphatase to remove phosphate group to prevent unwanted internal binding .so why dont we use any enzyme which can remove OHgroup from 3end

Q.

The mineral necessary for the coagulation of blood is

1. Sodium

2. Calcium

3. Potassium

4. Chlorine

Q.

What Is Factor VIII in Blood Clotting?

Q. Sickle-cell anaemia is caused

1. when valine is replaced by glutamic acid in the beta polypeptide chain
2. when glutamic acid is replaced by valine in the beta polypeptide chain
3. when glutamic acid is replaced by valine in the alpha polypeptide chain
4. when valine is replaced by glutamic acid in the alpha polypeptide chain

Q. The process to stop the flow of blood is called

1. erythropoiesis
2. hematopoiesis
3. coagulation
4. hemostasis

Q.

Mark the pair of substances among the following which is essential for coagulation of blood.
(a) heparin and calcium ios
(b) calcium ions and platelet factors
(c) oxalates and citrates
(d) platelet factors and heparin

Q. Which are III and VII factors responsible for blood clotting?

1. Thromboplastin, Proaccelerin
2. Thromboplastin, Proconvertin
3. Prothrombin, Antihaemophilic globulin (AHG)
4. Prothrombin, Calcium

Q.

What is the role of skin in the synthesis of vitamin D?

Q. Explain blood clotting with major events taking place in it.

Q.

Which enzyme aids in coagulation of blood.

Q. Which ion is required for the coagulation of blood?

1. Zinc
2. Copper
3. Magnesium
4. Calcium

Q.

During the coagulation of blood, vitamin K helps in the

1. Conversion of prothrombin to thrombin

2. Formation of prothrombin

3. Conversion of fibrinogen to fibrin

4. Formation of thromboplastin

Q. Assertion :Fibrins are formed by the conversion of inactive fibrinogens in the plasma by the enzyme thrombin. Reason: Plasma without fibrinogen and blood corpuscles is called serum.

1. Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
2. Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
3. Assertion is correct but Reason is incorrect
4. Both Assertion and Reason are incorrect

Q. What happens if blood platelets are absent in blood?

Q. Explain clotting of blood.

Q. Which of the following is / are wrong about blood clotting?
A. Fibrinogen $\stackrel{Thromboplastin}{\to }Thrombin$
B. Injured tissue + blood Platelets $\to$ Release thromboplastin
C. Prothrombin $\stackrel{Thrombin}{\to }$ fibrin
D. Fibrin + Red Blood corpuscles $\to$ Blood clot

1. A and C
2. C only
3. A only
4. B and C

Q. Who is going to suffer more from the sickle cell anaemia, the males or the females or both males and females equally? Why?

Q. The following belong together except which one?

1. white blood cell
2. macrophage
3. red blood cell
4. platelet

Q. Blood does not clot inside the blood vessels due to the presence of

1. Thrombin
2. Heparin
3. Fibrinogen
4. Vitamin K

Q. When blood is taken out, anticoagulants like oxalate/sodium citrate can be added to prevent blood clotting. These anticoagulants work by

1. Preventing action of blood clotting factor IV
2. Promoting the action of heparin
3. Preventing action of blood clotting factor III
4. Preventing action of heparin

Q. ________ are the blood cells, whose decrease in number can affect the clotting of blood.

1. Erythrocytes
2. Leucocytes
3. Thrombocytes
4. Both a and b