1
Question
Enzyme responsible for replication of HIV in macrophages is
Enzyme responsible for replication of HIV in macrophages is
Open in App
Solution
The correct option is A Reverse transcriptase
HIV :
HIV (Human Immuno deficiency Virus) is a retrovirus which contains two single stranded RNAs and reverse transcriptase enzymes. It causes AIDS. HIV infects and destroys helper T-lymphocytes and macrophages in the human body which weakens the immune system.
Macrophages :
Macrophages are formed from the monocytes. They are long-lived and strongly phagocytic (cell eating) to a wide variety of particulate materials such as microorganisms, dead cells, debris etc.
RNA polymerase :
RNA polymerase is an enzyme that copies a DNA sequence into an RNA sequence by the process of transcription.
DNA ligase :
DNA ligase is the enzyme that creates the phosphodiester bond between the nucleotides of DNA fragments and joins them together. For example, it joins the adjacent Okazaki fragments during DNA replication.
DNA polymerase :
DNA polymerases are enzymes that form long polymers of nucleotides for forming new copies of DNA.
Reverse transcriptase :
Reverse transcriptase is an enzyme that helps in the formation of DNA from RNA by reverse transcription. For example, HIV inserts its RNA in the host cell and the viral reverse transcriptase enzyme converts the RNA of HIV into viral DNA. The viral DNA gets integrated into the host genome and directs the host cell to assist the formation of viral RNA molecules that helps in forming viral proteins using host ribosomes.
Final answer :
(d) Reverse transcriptase
HIV :
HIV (Human Immuno deficiency Virus) is a retrovirus which contains two single stranded RNAs and reverse transcriptase enzymes. It causes AIDS. HIV infects and destroys helper T-lymphocytes and macrophages in the human body which weakens the immune system.
Macrophages :
Macrophages are formed from the monocytes. They are long-lived and strongly phagocytic (cell eating) to a wide variety of particulate materials such as microorganisms, dead cells, debris etc.
RNA polymerase :
RNA polymerase is an enzyme that copies a DNA sequence into an RNA sequence by the process of transcription.
DNA ligase :
DNA ligase is the enzyme that creates the phosphodiester bond between the nucleotides of DNA fragments and joins them together. For example, it joins the adjacent Okazaki fragments during DNA replication.
DNA polymerase :
DNA polymerases are enzymes that form long polymers of nucleotides for forming new copies of DNA.
Reverse transcriptase :
Reverse transcriptase is an enzyme that helps in the formation of DNA from RNA by reverse transcription. For example, HIV inserts its RNA in the host cell and the viral reverse transcriptase enzyme converts the RNA of HIV into viral DNA. The viral DNA gets integrated into the host genome and directs the host cell to assist the formation of viral RNA molecules that helps in forming viral proteins using host ribosomes.
Final answer :
(d) Reverse transcriptase
Suggest Corrections
0
Similar questions
View More
Join BYJU'S Learning Program
Explore more
Join BYJU'S Learning Program
