Question

How does DNA ligation work?

Answer 1

DNA ligation

1. DNA ligation is an important step during replication and repair of DNA damage.
2. DNA ligase enzyme brings about the ligation reaction.
3. ATP is required for ligation reaction.
4. The enzyme catalyzes the formation of a phosphodiester bond between the 3’ hydroxyl group of one nucleotide to the 5’ phosphate group of another nucleotide.