Question

If the sequence of the coding strand in a transcription unit is written as follows
5'-TGAACTGTAGCATGC-3'.
Find out the correct sequence of the m-RNA transcribed from it.

• A. 5'-UGAACUGUAGCAUGC-3'
• B. 3'-CGUACGAUGACAAGU-5'
• C. 3'-CGUACGAUGUCAAGU-5'
• D. 5'-UGACUGUAGCUUGC-3'

Answer 1

The correct option is A 5'-UGAACUGUAGCAUGC-3'

If the coding strand in a transcription unit is 5'-TGAACTGTAGCATGC-3'.
Then, it is known that the sequence of mRNA is same as the coding strand of DNA. However, in RNA, thymine is replaced by uracil. Hence, the sequence of mRNA will be
5'-UGAACUGUAGCAUGC-3'.