What is Griffith transforming principle ? Explain Griffith experiments on streptococcus pneumoniae while searching for genetic material.

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Solution

Based on his experiment with R and S strains of bacteria, Griffith came to the conclusion that the R strain bacteria had been transformed by the S strain. The R strain bacteria had inherited some transforming principle from the heat-killed strain that made them virulent.

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Similar questions

Q. (a) Explain the experiment performed by Griffith on Streptococcus pneumoniae. What did he conclude from this experiment?
(b) Name the three scientists who followed up Griffiths experiments.
(c) What did they conclude and how?

Q. To describe transforming principle, Frederick Griffith performed series of experiments by selecting two strains of Streptococcus pneumoniae namely S-strain (virulent) and R-strain (non-virulent).
Which of the following steps does not describe this experiment?
[0.7 mark]

Q. Choose the right combination of scientists and the organisms used for their experiments
i. Griffith - Streptococcus pneumoniae, mice
ii. Griffith - Bacteriophage, mice
iii. Hershey - Chase - E.coli,

T_{2}

bacteriophage
iv. Hershey - Chase - Streptococcus pneumoniae,

T_{2}

bacteriophage

Q. Which of the following is the true reference to transformation in bacteria?
(I) Transfer of genetic material is mediated by 'F' factor.
(II) Uptake of naked DNA fragments from surrounding environment and the expression of that genetic information in the recipient cell.
(III) Transformation experiments were the basis to propose the chromosomal theory of inheritance.
(IV) Transformation was discovered by Frederick Griffith in Streptococcus pneumoniae.

In his transforming experiment on mice, Griffith has taken two strains of streptococcus pneumonia, R-stain and s-strain. In which of the following case mice will remain alive?

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