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Question

50% of the lymphoid tissue in the human body is constituted by the

A
thymus
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B
spleen
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C
MALT
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D
lymph nodes
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Solution

The correct option is C MALT
Lymphoid organs are the specialised organs in the body composed of lymphoid tissue that provides the ideal environment for the production, maturation and proliferation of lymphocytes.

Primary lymphoid organs like the bone marrow and the thymus are the sites of origin and maturation of the lymphocytes. The secondary lymphoid organs are the sites where the lymphocytes migrate after maturation, interact with antigens (foreign substances that trigger immune responses in the body) and proliferate or multiply by cell division and differentiate into various cell types.

The spleen is a secondary lymphoid organ located just beneath the diaphragm, in the upper left abdominal cavity, and posterior to the stomach. It helps in sensitisation (identification of antigen) and proliferation of lymphocytes on exposure to antigens. It also acts as a reservoir for erythrocytes in the body and helps to filter blood by trapping foreign substances. It is also the site for destruction of worn out erythrocytes (RBCs) in the body.

The mucosa-associated lymphoid tissue (MALT), is a diffused system of small amounts of secondary lymphoid tissue found in the mucosal lining of the gastrointestinal tract, respiratory tract and urogenital tract. It constitutes about 50% of the lymphoid tissue in the human body. MALT is rich in lymphocytes such as T cells (produced in bone marrow but mature in the thymus) and B cells (produced in bone marrow and also mature in the bone marrow), macrophages (phagocytic cells that can engulf and digest foreign bodies), etc to fight with antigens passing through the mucosal epithelium.

Lymph nodes are bean-shaped masses of lymphoid tissue that are found in association with the lymphatic vessels. They are mostly found concentrated near junctions of the major lymphatic vessels. The lymph nodes serve as filters for the blood, providing sites where foreign antigens can be trapped and exposed to cells of the immune system for destruction.

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