Krebs Cycle

Q.

What is the metabolic fate of pyruvate?

Q. The complete oxidation of one pyruvate by the stepwise removal of hydrogen atoms produces:

1. Two molecules of $FAD{H}_2$
2. Two molecules of $GTP$
3. Two molecules of $NADP{H}_2$
4. Three molecules of $C{O}_2$

Q. The end product of citric acid/Krebs cycle is

1. citric acid
2. lactic acid
3. pyruvic acid
4. ${\mathrm{CO}}_2+H_{2}O$

Q.

What is the end product of TCA cycle?

Q.

How is TCA cycle regulated?

Q. Which statement is wrong for Krebscycle ?

1. There are three points in the cycle where NAD+ is reduced to NADH + H+
2. There is one point in the cycle where FAD+ is reduced to ${\mathrm{FADH}}_2$
3. During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised
4. The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid

Q. The first compound to enter TCA cycle along with Acetyl CoA is

1. oxalo succinic acid
2. citric acid
3. cis-aconitic acid
4. oxaloacetic acid

Q.

The number of ATP molecules produced by ETS from Krebs intermediates after a single turn of the cycle is completed is:

Q.

Does anaerobic respiration use the TCA cycle?

Q. What amount of energy is released from glucose during lactic acid fermentation:

1. More than $18\%$
2. Less than $7\%$
3. Approximately $15\%$
4. About $10\%$

Q.

What type of phosphorylation occurs in glycolysis?

Q.

Which metabolic pathway produces the most ATP?

Q.

What Is the Intermediate of TCA Cycle?

Q.

Does TCA Cycle require oxygen?

Q. ${\mathrm{FADH}}_2$ is produced in Krebs-cycle from

1. isocitrate
2. 𝝰-ketoglutarate
3. succinate
4. malate

Q.

Does glycolysis take place in the mitochondria?

Q.

How many TCA cycles are required during the complete oxidation of 2 sucrose?

Q. Krebs cycle begins with ________.

1. Condensation of acetyl-CoA with OAA and H₂O to yield citric acid

2. Conversion of OAA into citric acid through oxidation of NAD⁺

3. Oxidative decarboxylation of pyruvic acid to acetyl COA

4. Cleavage of succinyl COA into succinic acid and coenzyme A.

Q. The statement which is incorrect with respect to enzyme action is:

1. Addition of a lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate
2. The substrate binds with the enzyme at its active site
3. A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate
4. Malonate is a competitive inhibitor of succinic dehydrogenase

Q. Acceptor of acetyl CoA in Krebs cycle is

1. malic acid
2. fumaric acid
3. 𝝰- ketoglutaric acid
4. oxaloacetic acid

Q. When one molecule of glucose is completely oxidised during aerobic respiration, how many molecules of carbon dioxide are released due to tricarboxylic acid cycle?

1. Two
2. Three
3. One
4. Four

Q. Final decarboxylation in Krebs cycle occur between

1. citric acid and 𝝰-ketoglutaric acid
2. 𝝰-ketoglutaric acid and succinic acid
3. succinic acid and malic acid
4. malic acid and oxalo acetic acid

Q. From the following options, identify the 5C intermediate compound in the TCA cycle.

1. Citric acid
2. Succinyl CoA
3. $\alpha$-ketoglutaric acid
4. Fumaric acid

Q.

What Is the starting material for glycolysis?

Q. Read the assertion and reason carefully to mark the correct option in question.
Assertion: Glycolysis is the first step of respiration in which glucose completely breaks into $C{O}_2$ and $H_{2}O$.
Reason: In this process there is net gain of twenty four molecules of ATP.

Q. _______________ is the only enzyme of the TCA cycle located in the inner mitochondrial membrane.

1. Lactate dehydrogenase
2. Isocitrate dehydrogenase
3. Succinate dehydrogenase
4. Malate dehydrogenase

Q.

The overall goal of glycolysis, Krebs’ cycle, and the electron transport system is the formation of

1. sugars

2. ATP in one large oxidation reaction

3. ATP in small stepwise units

4. nucleic acids

Q. Which among the following statement is wrong for Krebs’ cycle?

1. There is one point in the cycle where FAD is reduced to ${\mathrm{FADH}}_2$.
2. During conversion of succinyl CoA to succinic acid, a molecule of GTP is synthesised.
3. The cycle starts with condensation of acetyl group (acetyl CoA) with pyruvic acid to yield citric acid.
4. There are three points in the cycle where ${\mathrm{NAD}}^{+}$ is reduced to NADH (reduced nicotinamide adenine dinucleotide) + $H^{+}$

Q. The complete oxidation of one pyruvate by the stepwise removal of hydrogen atoms produces:

1. Two molecules of $FAD{H}_2$
2. Three molecules of $C{O}_2$
3. Two molecules of $GTP$
4. Two molecules of $NADP{H}_2$

Q. In the TCA cycle, isomerisation of citrate is followed by how many decarboxylation(s) to form succinic acid?

1. 2
2. 3
3. 1
4. 4