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Question

Given below is the pedigree of sickle cell anaemia, in a family :


In this the RBC of both parents will be :

A
Sickle shaped
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B
Both normal & sickle shaped
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C
Cannot be determined
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D
Normal
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Solution

The correct option is B Both normal & sickle shaped
According to given pedigree analysis, both the parents are normal but have affected offspring that means both the parents must be carrier of sickle cell anemia gene.

Sickle cell anemia is autosomal recessive disorder so HBs gene is present in heterozygous form in parents so parents will have both normal and sickle cell shaped RBCs.

The correct answer is "option C"

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