Question

How many short polypeptide chains are seen in insulin?

Answer 1

Human insulin:

1. Insulin is made up of two short polypeptide chains, A and B, that are joined together by disulfide bridges.
2. Human insulin is made up of 51 amino acids that are organized into two polypeptide chains: A (21 amino acids) and B (30 amino acids).
3. Insulin is used to treat diabetes and is produced by a pro–hormone found in humans.
4. Because prohormones contain an extra stretch known as the C peptide, they must be processed to become fully mature and functional hormones.
5. C peptide is not found in mature insulin and is removed during the maturation process that converts proinsulin to insulin.