In the mechanism of action of a protein hormone, one of the second messengers is
A
Gastrin
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B
Insulin
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C
T3
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D
Cyclic AMP
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Solution
The correct option is D Cyclic AMP Mechanism of hormone action:
Hormones function by binding to their receptors which are located on the target site, to form the hormone receptor complex. The receptors are usually located either on the plasma membrane (membrane receptors) of the targets or inside the cell as in nucleus (intracellular receptors).
Water soluble hormones bind to membrane receptor complexes. This binding generates other molecules like Ca++, cAMP etc. which act as secondary messengers. These secondary messengers drive biochemical and physiological changes in the cell.
Lipid soluble hormones enter the cell by crossing the plasma membrane and bind to intracellular receptors to form hormone-receptor complex. Insulin, T3, gastrin:
Insulin, T3 and gastrin are hormones and not secondary messengers.