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Question
Predict the product of the Claisen schmidt reaction of the given substrate.
Predict the product of the Claisen schmidt reaction of the given substrate.
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Solution
The correct option is A
Claisen Schmidt reaction is a cross aldol condensation of ketone with aldehyde of no α-Hydrogens.
Mechanism of Claisen Schmidt reaction:
1. Formation of enolate ion: The base will abstract the α-hydrogen and forms a enolate.
2. Addition of enolate: The enolate will attack the carbonyl carbon of aldehyde to form aldol.
3. Dehydration: Water is removed from the aldol to form α,β− unsaturated ketone.
Claisen Schmidt reaction is a cross aldol condensation of ketone with aldehyde of no α-Hydrogens.
Mechanism of Claisen Schmidt reaction:
1. Formation of enolate ion: The base will abstract the α-hydrogen and forms a enolate.
2. Addition of enolate: The enolate will attack the carbonyl carbon of aldehyde to form aldol.
3. Dehydration: Water is removed from the aldol to form α,β− unsaturated ketone.
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