Question

Salicin (structure given below) is a glycoside, found in the bark of willow tree, used in relieving pain. Observe the following reaction of salicin.


The correct statement(s) is/are:

• A. P is D-glucose
• B. Q is 2-hydroxybenzylalcohol
• C. Q can be converted to a modern analgesic (pain killer), aspirin
• D. The above reaction occurs through a carbocation intermediate

Answer 1

Answer: (A), (B), (C), (D)

The above reaction occurs through a carbocation intermediate


Q upon oxidation with alkaline $KMn{O}_4$ followed by acetylation with excess of $A{c}_{2}O$ furnishes aspirin.