4n=2n×2n thus the only prime in the factorisation of 4n is 2 and 2 and the uniqueness of fundamental theorem of arithmetic guarantees that there are no other primes in factorisation of 4n except 2 and 2.
If the number 4n for any n, ends with digit zero then it has to be divisible by 5 and 2 both that is prime factorisation of 4n has to conatin primes 5 and 2.
But this is not possible as mentioned above
So there is no natural number n for which 4n ends with digit 0.