Question

The amino acid binding site of tRNA is

• A. anticodon loop
• B. T$\psi$C loop
• C. DHU loop
• D. 3’ end

Answer 1

The correct option is D 3’ end

Transfer RNA or tRNA is also known as soluble or supernatant RNA or adaptor RNA. 15% of the total cellular RNA is tRNA. tRNA consists of many different sites-

Amino acid acceptor arm: At 3’ end, 5’CCA3’ protrudes with OH at the tip, which is the site for the attachment of the amino acid.

DHU or D-loop: This loop contains 8-12 bases with unusual pyrimidine nucleotide dihydrouridine. It is the largest loop. It is a binding site for aminoacyl synthetase enzyme.

T$\psi$C loop: It contains the ribosome recognition site and has modified residue pseudouridine.

The anticodon loop is situated opposite to the amino acid accepting arm and is responsible for recognising and attaching to the specific codon of mRNA.