The pedigree below tracks Duchenne Muscular Dystrophy (DMD) through several generations. If individuals I-1 and I-2 had another son, what is the chance that he would have DMD?
A
0%
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B
25%
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C
50%
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D
100%
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Solution
The correct option is D100% As from pedigree DMD is an X linked recessive disease which will be seen in males mainly. As I-2 is affected she can pass only recessive gene and all sons will be affected and daughters will be carrier.