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Question

The pedigree below tracks Duchenne Muscular Dystrophy (DMD) through several generations.
If individuals I-1 and I-2 had another son, what is the chance that he would have DMD?

A
0%
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B
25%
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C
50%
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D
100%
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Solution

The correct option is D 100%
As from pedigree DMD is an X linked recessive disease which will be seen in males mainly. As I-2 is affected she can pass only recessive gene and all sons will be affected and daughters will be carrier.

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