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Question
What converts pyruvate to acetyl-CoA?
What converts pyruvate to acetyl-CoA?
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Solution
Pyruvate is converted to acetyl-CoA with the help of the enzyme pyruvate dehydrogenase complex.
- It is the process of oxidative decarboxylation whereby a carbon dioxide molecule that occurs in the citric acid cycle.
- The pyruvate dehydrogenase complex consists of three enzymes and five coenzymes.
- This reaction is carried out in the mitochondrial matrix.
- The overall reaction is: 2Pyruvate + 2NAD+ + 2CoA ⇢ 2Acetyl-CoA + CO2 + 2NADH
Pyruvate is converted to acetyl-CoA with the help of the enzyme pyruvate dehydrogenase complex.
- It is the process of oxidative decarboxylation whereby a carbon dioxide molecule that occurs in the citric acid cycle.
- The pyruvate dehydrogenase complex consists of three enzymes and five coenzymes.
- This reaction is carried out in the mitochondrial matrix.
- The overall reaction is: 2Pyruvate + 2NAD+ + 2CoA ⇢ 2Acetyl-CoA + CO2 + 2NADH
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