Question

What is a point mutation example?

Answer 1

Point mutation

1. When a single base pair is added, removed, or modified in a genome, it is called a point mutation.
2. Due to substitution, just one base pair of DNA is changed in a point mutation.
3. Substitution, deletion, and insertion are the three forms of point mutations.
4. One example of a point mutation is sickle-cell anaemia.
5. A point mutation in haemoglobin's -globin chain causes sickle-cell anaemia.
6. As a result, in the sixth position, the hydrophilic amino acid glutamic acid is substituted.
7. A point mutation can develop when a double-stranded DNA molecule creates two separate single strands.
8. Point mutations can also be caused by DNA modification, such as exposure to X-rays or UV light.