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Pyranose and Furanose

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What is meant by Active site?Which substrates gets attached to it?

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Q. Assertion : Enzymes have active sites that hold substrate molecule for a chemical reaction
Reason : Drugs compete with natural substrate by attaching covalently to the active site of enzyme

Q. Is allosteric inhibition only applicable in the lock and key mechanism?
Since the induced fit theory tells that the substrate can actually induce a change in the active site of the enzyme, hence even if the inibitor attaches itself to the enzyme, the substrate can attach to it (by changing the shape of the active site).

Q. Substrates bind to the active sites of an enzyme by interactions like :

Q. When drugs attach to allosteric sites on enzymes, the shapes of active sites radically are affected so that the substrate molecules cannot recognise the active sites.

Q. Drugs which act as competitive inhibitors, preferentially attach to the active sites prior to substrate molecules.
If this is true enter 1, if false enter 0.

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Pyranose and Furanose

Standard XII Biology

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