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Question

What is the negative feedback mechanism for the regulation of hormone secretion?


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Solution

Hormones:

  1. Hormones are molecules that specialized glands synthesize and generate in order to govern and regulate the functioning of certain cells and organs.
  2. They regulate several physiological systems as well as psychological wellbeing.
  3. They are also crucial in maintaining the body's homeostasis.
  4. Hormones are released by the endocrine system's glands.

Negative feedback mechanism:

  1. Negative feedback is the primary regulator of hormone synthesis and release (Short-Loop, long-loop negative Feedback).
  2. In negative feedback systems, a stimulus causes a substance to be released; once the substance reaches a specific level, it sends a signal that prevents the further release of the material.
  3. Hormones secreted from one gland regulate the release of other hormones from another gland.
  4. It then regulates the endocrine gland's hormone production.
  5. Furthermore, hormone release can be controlled by a chemical generated by target tissue in reaction to hormone or by the plasma level of hormone.
  6. The concentration of hormones in the blood is therefore kept within a restricted range.
  7. The anterior pituitary gland, for example, instructs the thyroid to release thyroid hormones.
  8. Increasing blood levels of these hormones then provide feedback to the hypothalamus and anterior pituitary, inhibiting further communication to the thyroid gland.


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