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Question

What Represents Lock And Key In The Lock And Key Hypothesis?


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Solution

The Lock And Key Hypothesis:

  1. The lock and key hypothesis states that the substrate fits perfectly into the enzyme, like a lock and a key.
  2. It was suggested by Emil Fisher in 1894. Enzymes perform their action by combining with a specific part of the substrate molecule.
  3. It is suggested that each enzyme has on its surface a precise place called the active site to which substrate molecules bind.
  4. This is due to the unique shape of the active site into which only some specific substrate molecules will fit.
  5. The substrate molecules combine with the enzyme to form an enzyme-substrate complex.
  6. The shape of the active site ensures that only those substrate molecules with a complementary structure will combine with the enzyme like a lock and its key.
  7. The substrate can be compared to a lock and the enzyme to a key.

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