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Question

When the skin is cut, the blood form clot. In which order would the components of the blood involve in the process of clot formation?


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Solution

  • The injured tissue cells and platelets disintegrate at the site of injury and release a substance known as thrombokinase or thromboplastin. ​
  • The thrombokinase acts as an enzyme which converts prothrombin (inactive) of the plasma into thrombin (active), with the help of calcium ions present in the plasma.​
  • In the presence of calcium ions, the soluble fibrinogen of the plasma is converted to insoluble fibrin by thrombin. ​
  • This fibrin forms a network of threads at the injury site. ​
  • Along with RBCs, these threads make a trap to form a clot at the site of injury which prevents further bleeding.​

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