What is the Full form of AML?
The full form of AML is Acute Myeloid Leukemia. It is a form of blood cancer that develops in the bone marrow, in which the myeloid cells or immature blood cells (myeloid cells) are precursors to other blood cells such as red blood cells (RBC), platelets, white blood cells(WBC) are affected. It triggers leukemic blasts to mutate in the myeloid cells and shape. Thus, the development of normal cells is impaired. Ultimately, there would be a deficiency of RBC, WBC and platelets in the affected person’s body.
The other names of AML are acute non-lymphocytic leukaemia or acute myelogenous leukaemia, or acute myeloblastic leukaemia. Based on the form of leukaemia cells found in the bone marrow blood, there are distinct forms of AML. Adverse modifications or mutations cause AML in myeloid cell DNA genes that are found in the bone marrow. It is not understood the real reason for such mutations.
Symptoms of AML
- Swollen lymph nodes
- Bone pain
- Frequent infections
- Nosebleeds
- Pale skin
- Fever
- Shortness of breath
- Bleeding gums
Risk Factors
- It is more common among people 65 years of age or older.
- Men are more likely than females to develop AML.
- AML growth is more likely among those exposed to very high doses of radiation, such as those who have survived nuclear reactor accidents.
- Benzene and many other cancer-causing chemicals are found in cigarette smoke.
- The risk of AML may be increased by other blood disorders, including myelodysplasia & myelofibrosis.
- Genetic conditions, including Down syndrome.
- Exposure to certain chemical substances, like benzene.
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