NASA stands for National Aeronautics and Space Administration and the full form of ISRO is the Indian Space Research Organisation.

The basic difference between ISRO and NASA is as follows –

ISRO	NASA
A research agency	A space administration agency
Established in 1969	Established in 1958
Mostly based on a development-oriented missions like communication, weather forecasting satellites, etc	Mostly based on research-oriented missions
Built India’s first satellite, Aryabhata	The first agency to put a man on the moon
ISRO superseded Indian National Committee for Space Research (INCOSPAR)	NASA superseded National Advisory Committee for Aeronautics (NACA)
Achievements – Mars orbiter mission (MOM) – India became the first nation to reach Mars in its first attempt. PSLV C37 – launched 104 satellites from a single rocket. Chandrayaan – India’ s first space mission to moon in 2008	Achievements- NASA has launched 1091 unmanned space satellites and 109 manned missions to different planets in the solar system. Apollo 1 – 1st spaceflight to moon (Neil Armstrong and Buzz Aldrin) landed on moon in 1969 Hubble space telescope – biggest telescope launched in lower orbit of the earth in 1990.

Related Links
Satellite Launch Vehicle Program	Juno Mission – NASA Space Probe to Jupiter
NASA and Axiom Space – Ax-1 Mission	NISAR – NASA-ISRO Synthetic Aperture Radar Mission
Gaganyaan Mission	List of Indian Satellites – (1975-2021)