MCQs on Lysosomes

  1. Which of the following organelle is called the “suicidal bags” of the cell?
  2. (a) Cytoplasm

    (b) Lysosomes

    (c) Mitochondria

    (d) Endoplasmic reticulum

    Sol:(b) Lysosomes.

  3. The lysosomal membrane is rich in ___________.
  4. (a) Sterols

    (b) Cardiolipin

    (c) Sialic acid

    (d) All of the above

    Sol:(c) Sialic acid.

  5. In which of the following cells Lysosomes are absent?
  6. (a) Animal cells

    (b) Erythrocytes

    (c) Hepatocytes

    (d) Muscles cells

    Sol: (b) Erythrocytes.

  7. What is the pH of a lysosome?
  8. (a) Acidic

    (b) Basic

    (c) Neutral

    (d) Depends on the cell type

    Sol: (a) Acidic.

  9. Which of the following enzymes are used as a marker for the lysosomes?
  10. (a) Phospholipase

    (b) Acid phosphatase

    (c) Pyruvate dehydrogenase

    (d) Succinate dehydrogenase

    Sol: (b) Acid phosphatase.

  11. Which of the following techniques are used in the isolation of Liposomal fractions?
  12. (a) Electrophoresis

    (b) Ultracentrifugation

    (c) Sucrose density gradient centrifugation

    (d) All of the above

    Sol: (c) Sucrose density gradient centrifugation.

  13. Which of the following are the functions of lysosomes?
  14. (a) Autolysis

    (b) Autophagy

    (c) Digestion

    (d) All of the above

    Sol: (d) All of the above.

  15. Which of the following statements are true about the acidic pH of lysosomes?
  16. (a) Presence of anabolic enzymes

    (b) Deposition of waste materials

    (c) Presence of hydrolytic enzymes

    (d) All of the above

    Sol: (a) Presence of anabolic enzymes.

  17. Lysosomes are involved in___________.
  18. (a) Digestion

    (b) Intracellular digestion

    (c) Extracellular digestion

    (d) Both intracellular and extracellular digestion

    Sol: (d) Both intracellular and extracellular digestion.

  19. Which of the following organelle is called the perinuclear dense bodies?
  20. (a) Nucleolus

    (b) Lysosomes

    (c) Peroxisome

    (d) All of the above

    Sol: (b) Lysosomes.

  21. Which of the following staining techniques are used to locate the lysosomes?
  22. (a) Gamori stain

    (b) Bismarck stain

    (c) Osmium tetroxide

    (d) Janus Green Staining

    Sol: (a) Gamori stain.

  23. Which of the following biomolecules are the components of lysosomes?
  24. (a) Ribosomes and Matrix

    (b) Amino acid chain and tRNA

    (c) Phosphate esters and nucleases

    (d) Glyco protein and Carbohydrates

    Sol: (c) Phosphate esters and nucleases.

  25. Why are lysosomes considered the “garbage trucks” of a cell?
  26. (a) Because they transport materials between two cell organelles

    (b) Because they pump materials from outside to the inside of a cell

    (c) Because they remove all unwanted cellular materials

    (d) Because they transport materials from one cell to another

    Sol: (c) Because they remove all unwanted cellular materials.

  27. Which of the following organelles contains digestive enzymes that break down complex molecules?
  28. (a) Lysosome

    (b) Ribosome

    (c) Golgi Body

    (d) Mitochondria

    Sol: (a) Lysosome.

  29. Which of the following cells contain the most active lysosomes?
  30. (a) Skin cells

    (b) Brain cells

    (c) Intestinal cells

    (d) White blood cells

    Sol: (d) White blood cells

  31. Lysosomes are involved in _________.
  32. (a) Secretion

    (b) Respiration

    (c) Photosynthesis

    (d) Protein construction

    Sol:(a) Secretion.

  33. Name two diseases caused by lysosome malfunction?
  34. (a) Cancer

    (b) Alzheimer’s

    (c) Batten Disease

    (d) Aspartylglucosaminuria

    Sol: (d) Aspartylglucosaminuria.

  35. Lysosomes are often found at _________.
  36. (a) Leukocytes

    (b) Erythrocytes

    (c) Blood Platelets

    (d) Cells in the liver

    Sol: (a) Leukocytes.

  37. Lysosomes are membrane-bound vesicles that arise from the_________.
  38. (a) Golgi apparatus

    (b) Mitochondria

    (c) Ribosomes

    (d) Endoplasmic reticulum

    Sol: (a) Golgi apparatus

  39. How do lysosomes originate?
  40. (a) From the cytoplasm

    (b) Phospholipid bilayer

    (c) By budding off from the membrane of the trans-Golgi network

    (d) None of the above

    Sol: (c) By budding off from the membrane of the trans-Golgi network.

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