Difference between Estrogen and Progesterone

Estrogen and progesterone are steroid hormones that play an important role in regulating mammalian reproduction. They regulate the development and functioning of the uterus. They act by regulating the transcription of certain genes in the uterus.

Estrogen is the hormone that regulates the menstrual cycle while progesterone is the hormone that supports pregnancy. During pregnancy, these two work together and are responsible for the changes that take place during pregnancy.

Also Read: Sex Hormones

Let us look at the difference between estrogen and progesterone given in a tabular column below.

Estrogen vs Progesterone

Following are the important difference between estrogen and progesterone:

Estrogen Progesterone
Estrogen is a female hormone secreted by ovaries prior to ovulation.
Progesterone is a female hormone that is secreted by ovaries after ovulation
Follicle stimulating hormone (FSH) largely controls the secretion of estrogen
Luteinizing hormone (LH) largely controls the secretion of progesterone
During pregnancy, it induces enlargement of breasts and uterus
During pregnancy, it reduces contractility of the uterus and stimulates the growth of mammary glands. It also induces the growth of decidual cells.
Growing Grafian follicle produces estrogen
Corpus luteum produces progesterone
Estrogen in men in large quantities create unbalance
Progesterone work together with testerone and has a lot of benefits

While comparing estrogen and progesterone, we notice that a proper combination of estrogen and progesterone is necessary for a healthy menstrual cycle and pregnancy.

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