Guillain–Barré syndrome or GBS is a rare muscle weakness condition that occurs because of the damage caused to the peripheral nervous system by the immune system. It is a rapid-onset syndrome. People affected by GBS feel sensation changes or endure pain which is followed by muscle weakness starting from the hands and feet.
The symptoms of GBS develop over half a day to 2 weeks. During its acute phase, the disorder can also be life-threatening. About one-fourth of the people affected develop weakness in the breathing muscles and need mechanical ventilation. Some patients suffer changes in the autonomic nervous system functions and this can cause severe abnormalities in the blood pressure and heart rate.